This is a newsletter from NextBioForm, a center coordinated by RISE with the goal to deliver better formulations for biopharmaceuticals. From the long-term perspective, our goal is to create stable biopharmaceuticals that will improve the quality of life for patients.
Read past NextBioForm newsletters and subscribe here |
|
| The activities in NextBioForm and elsewhere are back on full speed after the summer holidays. We are very happy that Vinnova has granted funding of NextBioForm for another year. This gives us the opportunity to continue to successful collaborations developed in the past years. During 2024 we will continue the ongoing research and complement this with new activities and collaborations with other consortia. |
| Read more |
|
|
Vinnova, in collaboration with the Swedish Research Council (Vetenskapsrådet), is investing an additional 12 million SEK in three crucial centers for biological medicines, including NextBioForm. These three centers will receive extended funding in the coming year, each receiving an additional four million SEK.
Read more
|
|
|
| On Tuesday, September 5th, Nisha Tyagi defended her licentiate thesis titled "Live Biotherapeutics : importance of formulation and lyophilization parametersand an example of a clinical application" at the Swedish University of Agricultural Sciences in Uppsala. |
|
|
Since August, Stefan Roos has been elected as a member of the NextBioForms board. Stefan is an adjunct professor in microbial biotechnology at SLU in Uppsala, but he is also employed at BioGaia AB and is a co-founder and adjunct at Ilya Pharma AB. Both companies are part of NextBioForm.
Read more |
|
|
|
NextBioForm, together with SweDeliver, organizes the conference "New Horizons on Drug Delivery and Formulations" on November 27-29 2023 at Uppsala Konsert & Kongress in Uppsala.
Last day to register is November 3rd!
Read more |
|
|
|
This paper demonstrate the first successful coupling of synchrotron small angle X-ray scattering (SAXS) to asymmetrical flow-field flow fractionation (AF4) for in-online protein characterization. This coupling has potentially high impact, as it opens the possibility to characterize individual constituents of sensitive and/or complex samples, not suited for separation using other techniques, and for low electron density samples where high X-ray flux is required, e.g., biomolecules and biologics.
AF4 fractionates complex samples in native or close to native environment, with low shear forces and system surface area. Many orders of magnitude in size can be fractionated in one measurement, without having to reconfigure the experimental setup. We report AF4 fractionations with correlated UV and statistically adequate SAXS data of bovine serum albumin and a monoclonal antibody and evaluate SAXS data recorded for the two protein systems.
Link to the publication, published in in Analytical and Bioanalytical Chemistry (August 12, 2023)
|
|
|
